Corey Speers, MD, PhD

Dr. Speers is a tenured Professor at the University Hospitals Seidmand Cancer Center and Case Western Reserve University where he is the Vice Chair of Research, Co-director of the Breast Oncology Program, and director of the phase I clinical trials program. He completed his medical and graduate degrees in the MSTP program at Baylor College of Medicine and MD Anderson Cancer Center in Houston, TX before completing his residency and Holman Pathway training at the University of Michigan in Ann Arbor. After joining the faculty at the University of Michigan and transitioning to UH/CWRU as a physician scientist, he has continued his research exploring the biology of aggressive breast cancers, including inflammatory, lobular, and triple-negative breast cancer. His laboratory is interested in “bench to bedside” research that includes basic mechanistic studies, translational pre-clinical studies, and clinical research. His interest in targeted therapies include PARP-inhibitors, CDK 4/6 inhibitors, and androgen receptor antagonists as agents for radiosensitization. These preclinical studies have been foundational to completed or open clinical trials evaluating these combinations in women with aggressive forms of breast cancer. In addition, he leads a number of studies that focus on utilizing expression-based signatures to predict the need for treatment intensification and de-escalation in for breast cancer.

Disclosures:

• Employment: University Hospitals:Vice Chair of Research:Employee
• Compensation: Exact Sciences: Consultant, Compensation Payment-End Date: 09/01/2024
• Ownership: none
• Leadership: none