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Sep 30
Education

EDU 35 - Revisiting Post-Prostatectomy Salvage Radiation in the Age of Precision Oncology

08:00am - 09:00am PT

MODERATOR(S)

Emily Weg, MD - Weill Cornell Medicine

session DESCRIPTION

This session will cover updates and evolving data in treating biochemically recurrent prostate cancer post-prostatectomy. One speaker will cover fractionation: can we safely hypofractionate in the post-operative setting, or is the data more supportive of conventional fractionation? Several single institution studies have examined SBRT in this setting, is SBRT to the reconstructed post-RP pelvis ready for prime time? A second speaker will address field and timing: in the era of SPPORT and POP-RT, do we recommend pelvic RT for everyone? And in the era of PSMA PET, have we learned anything about local patterns of failure than enable us to refine out prostate fossa target? And, how "early" should early salvage radiation be - should we follow criteria from trials like RADICALS, or should we wait for a higher PSA to customize the field to a PSMA PET target? A third speaker from medical oncology will address the use of systemic therapy with salvage radiation: with Decipher and Artera AI, what tools should we be using to inform the ADT decision for these patients? And is there adequate data to add androgen receptor pathway inhibitors for high risk patients?

learning objectives

  1. Determine the most appropriate fractionation regimen to be used in the post-prostatectomy salvage radiation setting.
  2. Assess whether the pelvic nodes need to always be included in the post-prostatectomy salvage setting, and how to utilize PSMA PET data to inform the prostate bed target.
  3. Consider when to use hormone therapy for post-prostatectomy salvage radiation patients and which agents are most appropriate.

Credits

AMA PRA Category 1 Credits: 1.00

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