Shannon MacDonald, MD, FASTRO

I am the Medical Director at Southwest Florida Protons. Before 2025, I was an Associate Professor of Radiation Oncology at Harvard Medical School (HMS). I served as Director of the Base of Skull Service and Sarcoma Service, as well as a member of the Pediatric Service in the Department of Radiation Oncology at Massachusetts General Hospital (MGH). Previously, I also served as a member of the Breast Service from 2006 to 2018 and as Director of the Breast Service. My expertise lies in the treatment of breast, pediatric, and base-of-skull tumors and sarcomas with a technology called proton therapy. I have worked at Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and Boston Children’s Hospital, providing proton therapy for pediatric patients and consulting on proton therapy for some adults, while promoting collaboration and the appropriate utilization of proton therapy. Providing comprehensive care to patients and their families remains the most fulfilling aspect of my career. Leading with a shared leadership style and one that fosters communication, collegiality, and well-being is of great importance. I am currently in a primary investigator or clinical co-chair role for 2 large multi-institutional clinical trials. I am the Primary Investigator of a Children’s Oncology Group (COG) Trial for Central Nervous System (CNS) Germ Cell Tumors that opened in 2021 in COG sites in the United States, Canada, Australia, and New Zealand. I am Clinical Chair of The Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial.

Disclosures:

• Employment: Mass General Brigham:MD:Employee;Dana Farber Cancer Institute:MD:Employee;Boston Children's Hospital:MD:Employee;Newton Wellesley Hospital:MD:Employee
• Compensation: Ion Beam Asscociates: Education Meeting Faculty, Honoraria, Travel Expenses-End Date: present ;ICOTEC: Consultant, Education Meeting Faculty, Honoraria, Travel Expenses, Compensation Payment-End Date: present
• Ownership: none
• Leadership: none