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10:35 AM - 10:40 AM PT

1138 - ADAR1 Expression in CD8<sup>+</sup> T Cells Modulates Radiotherapy Response and Prognosis in Non-Small Cell Lung Cancer via Disrupting Mitochondrial Function
Speaker: Tian, Chen, PhD - Department of Radiation Oncology and Shandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical, Jinan, Shandong
10:40 AM - 10:45 AM PT

1139 - Tumor Immune Microenvironment Modulation by Single-Fraction vs. Multifraction SBRT in an Orthotopic NSCLC Mouse Model
Speaker: Bouchard, Lea, MD, MS - University of Sherbrooke, Sherbrooke, QC
2:30 PM - 2:40 PM PT

114 - Phase 3, Randomized, Placebo Controlled Clinical Trial of CAN-2409+Prodrug in Combination with Standard of Care External Beam Radiation (EBRT) for Newly Diagnosed Localized Prostate Cancer
Speaker: Gejerman, Glen, MD, MBA - Hackensack University Medical Center, Hackensack, NJ
10:45 AM - 10:50 AM PT

1140 - hnRNPA1 Impedes the Anti-Tumor Immune Response Effect via Competitively Inhibiting TRIM21-Mediated Ubiquitination and Degradation of CD155
Speaker: Zhang, Lu, MS, none - Chongqing University Cancer Hospital, Shapingba, Chongqing
10:50 AM - 10:55 AM PT

1141 - Conventional Fractionated Elective Nodal Irradiation Preserves Early Antitumor Immunity and Efficacy Compared to Hypofractionated Protocols
Speaker: Sato, Genki, MD - Kyoto University Graduate School of Medicine, Kyoto, Kyoto
10:55 AM - 11:00 AM PT

1142 - Focal Adhesion Kinase Targeting Enhances Anti-Tumor Immunity Following Conventionally Fractionated Radiation
Speaker: Leibowitz, Brian, PhD - University of Pittsburgh School of Medicine, Pittsburgh, PA
11:00 AM - 11:05 AM PT

1143 - Quantifying pan-cancer immune temperature to predict patient-specific radiation response and outcome
Speaker: Ojwang, Awino Maureiq, PhD - MD Anderson Cancer Center, Houston, TX
10:35 AM - 10:40 AM PT

1144 - Enabling Continuous Monitoring of <sup>225</sup>Ac-Based Targeted Alpha Therapy Biodistribution via Energy Calibration of a Wearable ?-Spectrometer
Speaker: McManus, Richard, BS - University of California, Berkeley, Berkeley, CA
10:40 AM - 10:45 AM PT

1145 - Fully Flexible Lattice Position Optimization and Motion-Robust Single-Field-Each-Peak Optimization for LATTICE Therapy
Speaker: Tong, Xin, PhD - Department of Radiation Oncology, University of Kansas Medical Center, Kansas City, KS
10:45 AM - 10:50 AM PT

1146 - A Single Automated VMAT Planning Framework for TBI, CSI and TMLI: Streamlining Workflow and Enhancing Plan Quality
Speaker: Simiele, Eric, PhD - University of Alabama at Birmingham, Birmingham, AL
10:50 AM - 10:55 AM PT

1147 - The Role of Skull Dosimetry in Minimizing Acute Hematologic Toxicities of Brain Metastasis Patients Receiving Radiotherapy and Immunotherapy
Speaker: Ma, Jiachun - Shandong Cancer Hospital and Institute, Jinan, Shandong
10:55 AM - 11:00 AM PT

1148 - Early Salivary Gland Shrinkage is Associated with an Increased Risk of Acute Xerostomia in Head and Neck Cancer Patients Following Radiotherapy
Speaker: Treechairusame, Teeradon, MD - Memorial Sloan Kettering Cancer Center, New York, NY