EDU 37 - Integrating Radiation Therapy with Novel Immunotherapies in the Management of Brain Metastases and Leptomeningeal Disease
MODERATOR(S)
Kamran Ahmed, MD - H. Lee Moffitt Cancer Center
session DESCRIPTION
With improved systemic therapy, the management of brain metastasis has become increasingly important. A number of immunotherapies and targeted agents have shown blood brain barrier penetration with a potential role in the upfront management of brain metastases and leptomeningeal disease. Given new systemic options for brain metastases, coordinated care between radiation oncologists, medical oncologists, neuro-oncologists, and neurosurgeons is critical to optimize intracranial control but also limit toxicity. In this session, a multidisciplinary panel will guide the audience through novel immunotherapies in the management of brain metastases and leptomeningeal disease and provide insight on sequencing, management of toxicities, and response assessment.
learning objectives
- Identify systemic agents with demonstrated intracranial activity and ongoing clinical trials.
- Optimize treatment sequencing with response assessment of novel immunotherapies.
- Identify ways in which to identify and potentially reduce risks of radiation necrosis alongside immunotherapies.
Credits
| AMA PRA Category 1 Credits: | 1.00 |
Presentations
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08:00am - 09:00am PT
Integrating Radiation Therapy with Novel Immunotherapies in the Management of Brain Metastases and Leptomeningeal Disease
Speaker: Kamran Ahmed, MD - H. Lee Moffitt Cancer Center, Tampa -
08:00am - 08:02am PT
Introductions
Speaker: Kamran Ahmed, MD - H. Lee Moffitt Cancer Center, Tampa -
08:02am - 08:17am PT
Systemic Immunotherapies in the Management of Brain Metastases
Speaker: Solmaz Sahebjam, MD - Johns Hopkins University, Washington -
08:17am - 08:32am PT
Vaccine Strategies in the Management of Leptomeningeal Disease
Speaker: Peter Forsyth, MD - H. Lee Moffitt Cancer Center and Research Institute, Tampa -
08:32am - 08:47am PT
Optimizing Radiation Delivery of Brain Metastases and Leptomeningeal Disease Alongside Immunotherapies
Speaker: Zachary Buchwald, MD, PhD - Emory Department of Radiation Oncology, Atlanta -
08:47am - 09:00am PT
Questions and Answers
Speaker: Kamran Ahmed, MD - H. Lee Moffitt Cancer Center, Tampa