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Sep 29
Education

EDU 42 - Radiation Wins: New Evidence and Evolving Strategies in Multiple Myeloma

12:30pm - 01:45pm ET

MODERATOR(S)

Joachim Yahalom, MD, FASTRO - Memorial Sloan Kettering Cancer Center

session DESCRIPTION

Dramatic innovations in systemic and inmunotherapy dramatically lengthened the survival of myeloma patients that could potentially benefit from local therapy. Yet, radiotherapy use remained stale and suppressed. More recently, emerging data of RT usage and efficacy in MM, supports a shift away from viewing RT as "palliation only" toward a more strategic role in the era of CAR T-cell therapy and bispecific antibodies. New datasets challenge long-standing assumptions regarding dose and fractionation, highlight the importance of timely and efficient local control for symptomatic, high-risk or refractory sites of disease, and raise questions about earlier intervention for extramedullary disease and oligoprogression — settings in which RT may meaningfully improve outcomes without compromising systemic therapy delivery. This session will bring together expert speakers representing all relevant modalities (radiation oncology, hematology and imaging) who were directly involved in the pivotal studies. Attendees will leave with actionable guidance on patient selection, integration with novel systemic therapies, contemporary RT dosing/fractionation, toxicity mitigation and future trial directions.

learning objectives

  1. Apply contemporary randomized data to identify when and how radiation therapy adds measurable value within multidisciplinary care, particularly in the context of novel systemic therapies.
  2. Communicate the role and benefits of radiation therapy more effectively to multidisciplinary partners, supporting aligned decision making that improves outcomes while minimizing toxicity.

Credits

AMA PRA Category 1 Credits: 1.00

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