EDU 17 - Spatially Fractionated Radiation Therapy (SFRT): Biological Mechanisms and Clinical Translation
MODERATOR(S)
Claire Vanpouille-Box, PhD - Weill Cornell Medical College
session DESCRIPTION
This educational session will focus on the biologic mechanisms and clinical translation of spatially fractionated radiotherapy (SFRT), including GRID and minibeam techniques. Speakers will present data demonstrating how spatially patterned radiation modulates tumor biology, vascular responses, and anti-tumor immunity, influencing treatment response. SFRT's unique peak-valley dose distribution affects tumor heterogeneity and the microenvironment, offering opportunities to enhance anti-tumor efficacy. Understanding how SFRT interacts with tumor biology and the immune system can inform novel strategies to improve patient outcomes and guide practical clinical implementation.
learning objectives
- Describe the biologic mechanisms underlying SFRT, including immune and microenvironmental effects.
- Identify approaches for clinical implementation of SFRT, including GRID and minibeam therapies.
Credits
| AMA PRA Category 1 Credits: | 1.00 |
Presentations
-
08:00am - 08:02am ETSpeaker: Claire Vanpouille-Box, PhD - Weill Cornell Medical College, New York
-
08:02am - 08:17am ETSpeaker: Mark Oldham, PhD - Duke University Medical Center, Durham
-
08:17am - 08:32am ETSpeaker: Heiko Enderling, PhD - The University of Texas MD Anderson Cancer Center, Houston
-
08:32am - 08:47am ETSpeaker: Michael Grams, PhD - Mayo Clinic, Rochester
-
08:47am - 09:00am ETSpeaker: Claire Vanpouille-Box, PhD - Weill Cornell Medical College, New York