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Sep 28
Education

EDU 22 - Endometrial and Cervical Cancer Case Discussion on Utilizing Molecular Data for Treatment Decisions

10:45am - 12:00pm ET

MODERATOR(S)

Katherine Tzou, MD - University of Colorado

session DESCRIPTION

Using a case-based approach, this session will discuss recent data and how to incorporate molecular data for treatment risk stratification and follow up for endometrial and cervical cancer patients. The cervix cancer case discussion will highlight how HPV ctDNA can be a tool for early recurrence detection and will also cover the recently published CALLA data showing how ctDNA predicted relapse and survival outcomes. The early-stage endometrial cancer case discussion will cover the PORTEC2 molecular data, the more recently identified significance of MLH1 promoter hypermethylation and the newly published PORTEC4 results. The session will also include a comparing and contrasting of the PORTEC 3 and more recently published GOG 258 molecular data using an advanced endometrial case discussion to help highlight how to utilize molecular data to optimize treatment approach.

learning objectives

  1. Be able to discuss how pathologic factors, such as molecular status, influence prognosis and treatment decisions.
  2. Discuss recent clinical trial data where molecular data was used for risk stratification or influenced gynecologic cancer patient outcomes.
  3. Describe how ctDNA can potentially be used to follow cervical cancer patients.

Credits

AMA PRA Category 1 Credits: 1.00

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