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9:25 AM - 9:30 AM ET

1242 - AKR1C3 Negatively Regulates the LGALS3/p62/NRF2 Axis to Inhibit Ferroptosis and Induce Radioresistance in Prostate Cancer
Speaker: Lyu, Feng, MD, PhD - Peking University First Hospital, Beijing, Beijing
9:30 AM - 9:35 AM ET

1243 - Radiation Enhances Efficacy of Trastuzumab Deruxtecan in HER2-Low Metastatic Breast Cancer via HER2 Upregulation
Speaker: Li, Qing, MD, PhD - Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland, OH
9:35 AM - 9:40 AM ET

1244 - Nanoray Pancreas: Biomarker Insights of NBTXR3 Activated by Radiotherapy (RT) for Locally Advanced or Borderline Resectable Pancreatic Cancer (LAPC or BRPC)
Speaker: Cargill, Kasey, MD, PhD - MD Anderson Cancer Center, Houston, TX
9:40 AM - 9:45 AM ET

1245 - AARS1/2-Mediated Histone Lactylation Drives an Immunosuppressive Tumor Microenvironment and Represents a Novel Target to Enhance Anti-PD-1 Therapy
Speaker: Liu, Mei - Cancer Center, Shandong University, Jinan, Shandong
9:45 AM - 9:50 AM ET

1246 - Radiotherapy under Low Glucose Triggers Disulfidptosis in SLC7A11-High Tumors by Limiting Pentose Phosphate Pathway-Derived NADPH
Speaker: Sun, Yajie, MD - Union Hospital Cancer Center, Tongji Medical College, HUST, Wuhan, Hubei
9:15 AM - 9:20 AM ET

1247 - Integrating Clinical and PET Radiomics Features for Pre-Therapy Cardiac Risk Prediction
Speaker: Panchal, Devanshu, PhD - Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA
9:20 AM - 9:25 AM ET

1248 - External Validation and Development of Radiomics Models for Radiation Pneumonitis after Chemoradio-Immunotherapy in Locally Advanced NSCLC
Speaker: Ebrahimpour, Leyla, PhD - Memorial Sloan Kettering Cancer Center, Middletown Township, NJ
9:25 AM - 9:30 AM ET

1249 - Predicting Late Genitourinary Toxicity after MR-Guided Prostate Stereotactic Radiation Therapy (SBRT) through Integrating Fractional Dosimetry
Speaker: Qi, Xiangrong, PhD - Dept. of Radiation Oncology, Los Angeles, CA
3:40 PM - 3:50 PM ET

125 - Phase I Trial with Expansion Cohort of DNA-PK Inhibitor Peposertib and Intensity Modulated Radiation Treatment (IMRT) in Cisplatin-Ineligible Patients with Stage 3-4 Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)
Speaker: Samuels, Michael, MD - University of Miami Miller School of Medicine, Miami, FL
9:30 AM - 9:35 AM ET

1250 - Mid-Treatment CT Mean Density, Volume and Mass Changes as Early Response Biomarkers in Head and Neck Cancer Radiotherapy Using AI-Based Deformable Image Registration
Speaker: Nayak, Lopamudra, PhD - Memorial Sloan Kettering Cancer Center, New York, NY
9:35 AM - 9:40 AM ET

1251 - Interpretable Modeling of Dysphagia Risk after Head and Neck Re-irradiation
Speaker: Wang, Kai, PhD - University of Colorado Anschutz Medical Campus, Aurora, CO
9:40 AM - 9:45 AM ET

1252 - Predictors for Abdominal Acute Toxicity and Acute Care Utilization Following Liver EBRT
Speaker: Lavrova, Elizaveta, MD - UNC Health, Chapel Hill, NC